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The "Target Sign": Is it a Specific Sign of CNS Tuberculoma? Neuroradiology 38:547-550, Bargallo,J.,et al, 1996 See this aricle in Pubmed Article Abstract In brain lesions, the target sign has been defined as a central nidus of calcification or central enhancement surrounded by a ring of enhancement. It has been considered a pathognomonic finding of central nervous system (CNS) tuberculoma. The purpose of this report is to demonstrate that the target sign related to central enhancement is a nonspecific finding and may lead to erroneous diagnosis of CNS tuberculoma.

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